Monday, September 09, 2013

What is the meaning of Pharmaceutical chemistry? Concept and Definition of Pharmaceutical chemistry

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Definition, concept, meaning, what is Pharmaceutical chemistry


 Pharmaceutical chemistry

1. Concept of pharmaceutical chemistry

Pharmaceutical chemistry is one considered to be pharmaceutical, with deep roots in the chemistry and Sciences border with Pharmacology, studying the design, synthesis and development of molecules with biological activity and drugs for therapeutic purposes.
Medicinal chemistry aims the identification, synthesis and the development of new chemical compounds that are suitable for therapeutic use. This includes the study of existing drugs, their biological properties and their quantitative structure-activity relationship. She also studies the quantitative interactions among these molecules and its biological effects.
It's a very deep and complex discipline that combines knowledge of organic chemistry, quimica-fisica, combinatorial chemistry, bioinformatics, biochemistry, pharmacodynamics, Biopharmacy and pharmacokinetics. This discipline has had a marked development in base to establish molecular descriptors and seeded or molecular prototypes, to develop new bioactive molecules and establishing a correlation between the 3D molecular structure and bioactives from each structure attributes, this science has allowed amazing discoveries regarding the involvement of the chemistry of molecules in their pharmacological effects.


2. Definition of pharmaceutical chemistry

Pharmaceutical chemistry is the branch of this field of study that can tick therapeutic since it includes analysis, study, search and tuning of organic and inorganic compounds to be used in medicine. Pharmaceutical chemistry is one of the most direct applications in society, since its impact on this is so important that it represents one of the first variants discussed in finding a new element or component in the natural, is basically wonder if what's new that you are getting or synthesizing serves as a treatment for any disease.
The pioneers in medicinal chemistry as it is also known have been Charles Pfizer and Charles Erhart of Pfizer Inc.'s founding have sought healing and relief for various ills in the world, today its laboratories are the largest in the world, without leaving of side other pharmaceutical companies, but thanks to the methods of these two scientists were synthesized many elements such as iodine and camphor. Evils and infections that have attacked humanity at the time was that a group of scholars dedicated to find more cures than the extermination and the time, before the effects that had many plants in diseases, took the decision to synthesize these pills and remedies to everyone. Pharmaceutical chemistry has been very social since its inception, always in search for the solution to many evils.
Pharmaceutical chemistry works in the form of patterns, establishing a methodological framework according to each disease that exist in the world, from all the genetic information that has the virus or strain, you get a mirror effect with the molecule that synthesize to eradicate it, the pharmaceutical industry uses diseases itself to find the cure, through vaccines. Also, the human body comprises a winding field of study, because the effects that these persons have not always will be the same, because each has a different metabolism so the answer will be different in each who is task of pharmaceutical chemistry to create generic drugs, able to adapt to each metabolism.


3. Meaning of pharmaceutical chemistry

The pharmaceutical chemical or medicinal chemistry is one considered to be pharmaceutical, with deep roots in the chemistry and Sciences border with Pharmacology, studying the design, synthesis and development of molecules with biological activity and drugs for therapeutic purposes. Medicinal chemistry aims the identification, synthesis and the development of new chemical compounds that are suitable for therapeutic use. This includes the study of existing drugs, their biological properties and their quantitative structure-activity relationship. She also studies the quantitative interactions among these molecules and its biological effects (QSAR).1 the subject of studies molecules are mostly organic and even biotechnology, but (the cisplatin as anti-cancer, for example) can also be inorganic.

Features

It's a very deep and complex discipline that combines knowledge of organic chemistry, quimica-fisica, combinatorial chemistry, bioinformatics, biochemistry, pharmacodynamics, Biopharmacy and pharmacokinetics. This discipline has had a marked development in base to establish molecular descriptors and seeded or molecular prototypes, to develop new bioactive molecules and establishing a correlation between the 3D molecular structure and bioactives from each structure attributes, this science has allowed amazing discoveries regarding the involvement of the chemistry of molecules in their pharmacological effects.

Pharmaceutical chemistry

Pharmaceutical chemistry, while walking near the pharmacology, has its own lift that in past instances has been involved in course on thermodynamics and quantum physics and computer science, every time that tries to elucidate all the mechanisms and factors that are involved in ligand-receptor union.
Pharmaceutical chemistry is focused on the qualitative aspects of the measurements.

Specialization

Specialization usually come from doctoral studies in pharmacy (pharmaceutical chemistry) colleges and faculties of Chemistry (organic chemistry). He is usually said that a good chemical pharmacist is not only a good organic chemist, but that you must know topics of Pharmacology, bio-Pharmacy and biochemistry, so Pharmacy studies are very suitable to serve as a basis for these postgraduate studies.

Medicinal chemistry

Medicinal chemistry is a highly interdisciplinary science combining organic and inorganic chemistry with biochemistry, computational chemistry, pharmacology, the Pharmacognosy, molecular biology, statistics, and physical chemistry.
Undertakes study and apply all the traditional organic chemistry concepts to the development of substances that could contribute in one way or another to the pharmaceutical sciences regarding the biological effects that different substances chemical, usually heterocyclic, could have on the human body.

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